Info

🌱 來自: Hyperprolactinemia

Treatment of Hyperprolactinemia

• If asx (no HA, galactorrhea, hypogonadal sx) & microadenoma (<10 mm), follow w/ MRI
• If sx or macroadenoma (10 mm) options include:
  • Medical with dopamine agonist such as
    • cabergoline (70-100% success rate) or
    • bromocriptine (not as well tol); side effects include N/V, orthostasis, mental fogginess
  • Surgical: transsphenoidal surgery (main indications: failed or cannot tolerate medical Rx, GH cosecretion or neurologic sx not improving);
    • 10-20% recurrence rate
  • Radiation: if medical or surgical therapy have failed or are not tolerated