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🌱 來自: glycemic management in the ICU setting

NICE-SUGAR trial

March 26, 2009 N Engl J Med 2009; 360:1283-1297 DOI: 10.1056/NEJMoa0810625

• intensive (i.e., tight) control target of 81 to 108 mg per deciliter (4.5 to 6.0 mmol per liter), based on that used in previous studies,
• conventional-control target of 180 mg or less per deciliter (10.0 mmol or less per liter),

In this large, international, randomized trial, we found that intensive glucose control increased mortality among adults in the ICU: a blood glucose target of 180 mg or less per deciliter resulted in lower mortality than did a target of 81 to 108 mg per deciliter.