Info

🌱 來自: Clinical Pathway-of-breast cancer

Neoadjuvant chemotherapy for operable breast cancer patients

• Operable breast cancer preferred for neoadjuvant chemotherapy includes:

  • Triple negative breast cancer or HER2 positive cancer
    • with clinical T-stage ≧ cT2 or N-stage ≧ cN1
  • For locally advanced breast cancer patients
    • (≧ cT3 or cN2)
  • Larger primary tumor relative to breast size
    • in patients who desire breast conservation therapy

• Clips placement both at ↣ primary tumor and positive axillary lymph node(s) is → suggested for tumor localization before neoadjuvant chemotherapy

  • BCS/Mastectomy
  • Axillary management:
    • If cN0 both before and after C/T → SLNB
    • If cN1 become ycN0 after C/T, may consider SLNB + clipped node removal
    • If cN2 or cN3 before C/T → ALND