Etiology-acute liver failure

(J Hepatol 2015;62:S112)

• Drugs and toxins that cause acute liver failure

• Viral: HAV, HBV, HCV (rare), HDV + HBV, HEV (esp. if pregnant). In immunosupp: HSV (50% have skin lesions), EBV, VZV, CMV, HHV6

• Vascular: Budd-Chiari, ischemic hepatitis, hepatic sinusoidal obstruction syndrome

• Other: Wilson disease, pregnancy-related ALF (acute fatty liver, preeclampsia, HELLP), initial presentation of autoimmune hepatitis; idiopathic