General-renal replacement and dialysis

  • Acute indications:
    • see “AKI”;
    • choices CVVH vs. HD
  • Chronic indications:
    • timing of RRT initiation should factor in Pt QoL, uremic sx, risk of development of urgent/acute indications;
    • modalities PD vs. HD (no clear diff in outcomes)
  • Outcomes of ESRD:
    • death from CVD (50%),
    • infxn (30%),
    • withdrawal of care (20%)