Membranous nephropathy

(30%; CJASN 2017;12:938, JASN 2021;32:268):

Primary

  • Anti-PLA2R 70%,
  • THSD7A 5%,
  • other (EXT1-2, NELL1, Sema3B)

Secondary

  • infxn (HBV, HCV, HIV, syphilis)
  • autoimmune (eg, SLE)
  • carcinomas
  • drugs (NSAIDs, penicillamine).