definition of small lymphocytic lymphoma
(NEJM 2005;352:804; Blood 2008;111:5446)
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Monoclonal, functionally incompetent mature B lymphocytes;
CLL & SLL = same disease
- CLL: >5000/µL malignant cells;
- SLL: <5000/µL malignant cells
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Monoclonal B lympho-CYTOSIS:
- resembles but does not meet CLL criteria, observe