Acute treatment of Migraine

First-line medication

• NSAIDs (acetylsalicylic acid, ibuprofen or diclofenac potassium)

Second-line medication

• Triptans
• When triptans provide insufficient pain relief, combine with fast-acting NSAIDs

Third-line medication

• Ditans
• Gepants

Adjunct medications for nausea and/or vomiting

• Prokinetic antiemetics (domperidone or metoclopramide)