Info
type 1 diabetes mellitus
(Lancet 2018;391:2449):
參考➡️ Type 1 diabetes islet cell destruction; absolute insulin deficiency; ketosis in absence of insulin; prevalence 0.4%; usual onset in childhood but can occur throughout adulthood; ↑ risk if ⊕ FHx; HLA associations; anti-GAD, anti-islet cell & anti-insulin autoAb
Explain by ChatGPT
-Type 1 diabetes mellitus is a condition in which the pancreas does not produce enough insulin. -This can lead to ketosis (a build-up of ketones in the body) in the absence of insulin. -Type 1 diabetes mellitus is relatively rare, affecting around 0.4% of the population. -It usually starts in childhood, but can occur at any age. -There is an increased risk if there is a family history of the condition. -Type 1 diabetes mellitus is also associated with certain HLA types. -Autoantibodies against GAD, islet cells and insulin are often present.
窩的英文不太好
- 1 型糖尿病是一種胰腺不能產生足夠胰島素的疾病。 -在沒有胰島素的情況下,這會導致酮症(體內酮的積累)。
- 1 型糖尿病相對罕見,影響了大約 0.4% 的人口。
- 它通常從童年開始,但可以發生在任何年齡。
- 如果有家族病史,風險會增加。
- 1 型糖尿病也與某些 HLA 類型有關。
- 通常存在針對 GAD、胰島細胞和胰島素的自身抗體。