Consequences-of-Severe-Acid-Base-Disturbances

(NEJM 1998;338:26 & 107)

cardiovascular consequences-of-Severe-Acid-Base-Disturbances 󰒗

Respiratory

  • Acidemia (pH <7.20)
    • Hyperventilation, ↓ resp. muscle strength
  • Alkalemia (pH >7.60)
    • Hypoventilation

Metabolic

  • Acidemia (pH <7.20)
    • ↑ K (resp. > metab.), insulin resistance
  • Alkalemia (pH >7.60)
    • ↓ K, Ca, Mg, PO4

Neurologic

  • Acidemia (pH <7.20)
    • Δ MS
  • Alkalemia (pH >7.60)