Info

🌱 來自: chemotherapy protocol

MVAC

• Methotrexate 30 mg/m2 IV Push
• Vinblastine 3 or 4 mg/m2 IV Push
• Doxorubicin 30 mg/m2 IV Push
• Cisplatin 50 or 70 mg/m2 IVF over 60 mins (rate 180ml/hr at KFSYSCC)

Referece

• Sternberg CN, Yagoda A, Scher HI, et al. Methotrexate, vinblastine doxorubicin, and cisplatin for advanced transitional cell carcinoma of the urothelium: Efficacy and patterns of response and relapse. Cancer 64:2448-2458, 1989.
• Sternberg CN, de Mulder PHM, Schornagel JH, et al. Randomized phase III trial of high-dose-intensity methotrexate, vinblastine, doxorubicin, and cisplatin (MVAC) chemotherapy and recombinant human granulocyte colony-stimulating factor versus classic MVAC in advanced urothelial tract tumors: European organization for research and treatment of cancer protocol no. 30924. J Clin Oncol. 2001;19(10): 2638-2646.