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🌱 來自: Huppert’s Notes
Renal Formulas🚧 施工中
Renal Formulas
• Important renal concepts and formulas: See Table 6.1
TABLE 6.1 • Important Renal Concepts and Formulas
TABLE 6.2 • Urinalysis Tests and Interpretation
• Pearls about glomerular filtration rate (GFR):
- GFR is measured with exogenous substances (inulin or radioisotopes) or estimated with endogenous substances (creatinine or cystatin C)
- In clinical practice, estimated GFR (eGFR) is calculated using the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) formula, which has the best accuracy in persons with normal eGFR, or using the Modification of Diet in Renal Disease (MDRD) equation. These equations have largely replaced the Cockcroft-Gault equation.
- eGFR is most accurate when a patient is in a steady state (i.e., has a stable sCr). When interpreting eGFR, consider common scenarios that affect the result, such as muscle mass, medication effect (e.g., TMP/SMX), or dynamic states (e.g., early AKI).
- If eGFR accuracy is critical, consider calculating eGFR with cystatin C, a freely filtered molecule that is not affected by muscle mass.