Info

🌱 來自：graft_sources_in_absence_of_matched_related_donor

unrelated_donor

• BM or PBSC from URDs identified through NMDP

Advantages

• W/ improved HLA typing, outcomes w/ 8/8-matched URD have become closer to those w/ MRD (eg, Leukemia 2010;24:1276)

Disadvantages

• Higher GVHD vs. related, especially if mismatch
• Longer process of procuring graft
• Likelihood of matched URD highly dependent on race (NEJM 2014;371:339)