Info
organ_toxicities_of_hsct
- A result of direct regimen-related toxicities from conditioning Acute/Sub-acute:
- SOS/VOD, pulmonary (IPS, DAH), cardiac, & renal injury
- Late (chronic): Infertility, cataracts, 2° malignancies (below)
| Modality | Major organ affected |
|---|---|
| Radiation | Lungs, heart |
| Cyclophosphamide | Heart |
| Busulfan | Lungs |
| Etoposide | Liver |
| Carmustine | Lungs |
| Cytarabine | CNS, nervous tissue |
| Melphalan | Lungs, gastrointestinal |