Info

🌱 來自: leukemia and myeloproliferative neoplasms

chronic myelogenous leukemia (CML)

Epidemiology

• Myeloproliferative Neoplasm (MPN)
• 15-20% of adult leukemias,
• approx 5000 new cases/year in the United States, 1-2 cases per 100000 adults, median age 55-60
• 血細胞減少
• 骨髓發育 ✖ 不良
• 持續性外周血::單核細胞::增多
• 老年男性

Dx

• persistent (> 3 months) peripheral blood

  • monocytosis (> 1 × 109/L and > 10% of differential)

• definition of chronic myelogenous leukemia (CML)

• epidemiology and risk factors of chronic myelogenous leukemia (CML)

• disease classification and manifestations of chronic myelogenous leukemia (CML)

• diagnostic evaluation of chronic myelogenous leukemia (CML)

• biology of chronic myelogenous leukemia (CML)

• treatment of chronic myelogenous leukemia (CML)

• prognosis of chronic myelogenous leukemia (CML)

REF

Lancet2021;398:1914

Nabhan C, Rosen ST. Chronic Lymphocytic Leukemia: A Clinical Review. JAMA. 2014;312(21):2265. doi:10.1001/jama.2014.14553