Background of vasculitis
Classified
- by size of predominant vessel affected (Arthritis Rheum 2013;65:1); overlap of vessel size affected is common
- 看一下這張圖:
- 有很多部分會重疊:注意是所有種的都會影響到大中小,所以不能排除
Clinical manifestations
- based on size of vessels involved; specific symptom
- constitutional sx (low-grade fever, fatigue, weight loss, myalgias, anorexia)
- common to all from inflammatory response
Vasculitis is typically divided into 2 main categories:
- primary (idiopathic)
- secondary, caused by an underlying condition, such as an autoimmune process, infection, a neoplastic process, or certain medications
- Vasculitis can occur in any vessel type in any organ system of the body.
- It ranges in severity from a self-limiting, single-organ condition to a multiorgan disease that leads to end organ failure.