Background of vasculitis

Classified

  • by size of predominant vessel affected (Arthritis Rheum 2013;65:1); overlap of vessel size affected is common
    • 看一下這張圖:Distribution of vessel involvement
    • 有很多部分會重疊:注意是所有種的都會影響到大中小,所以不能排除

Clinical manifestations

  • based on size of vessels involved; specific symptom
  • constitutional sx (low-grade fever, fatigue, weight loss, myalgias, anorexia)
    • common to all from inflammatory response

Vasculitis is typically divided into 2 main categories:

  • primary (idiopathic)
  • secondary, caused by an underlying condition, such as an autoimmune process, infection, a neoplastic process, or certain medications
  • Vasculitis can occur in any vessel type in any organ system of the body.
  • It ranges in severity from a self-limiting, single-organ condition to a multiorgan disease that leads to end organ failure.