Info

🌱 來自: Blood Products and Indications

Platelets transfusion

• For plts <10k (NEJM 2010;362:600) due to chemo/abx.
• If <20k or if <50k w/ active bleeding.
• Variable pre-procedure.100k for neurosurgery. 1 U → ↑ plt ~30-60k.
• Single donor plt apheresis ↓ alloimmunization.
• Contraindic:
  • TTP/HUS,
  • HELLP,
  • HIT.
• Refractory if ↑ <5k 30-60′ post-plts.
  • Suggests consumption such as ITP, DIC, or alloimmunization → trial ABO-matched plts & give more.
  • If still refractory ✓ panel reactive Abs to assess utility of HLA-matched plts.