Antituberculous Medications

see also Antituberculous Treatment Regimens

*Risk of hepatitis ↑ w/ pre-existing liver disease. Consult ID, consider holding/replacing PZA or INH.

Isoniazid (INH)

Hepatitis (avoid EtOH), WARN: periph neuropathy (↓ risk by suppl. vit B6), drug-induced lupus

Rifampin (RIF)

Orange tint of body fluids, GI upset, hepatitis (avoid EtOH), hypersensitivity, fever, drug interactions

Pyrazinamide (PZA)

WARN: Hepatitis (avoid EtOH), hyperuricemia, arthritis

Ethambutol (EMB)

Optic neuritis

Streptomycin (SM)

Ototoxicity, nephrotoxicity

Amikacin (AMK)

Ototoxicity, nephrotoxicity

Quinolone (moxifloxacin, levofloxacin)

GI upset, tendinopathy, ↑ QTc