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Oritavancin of Important Antibacterial Drug Interactions

  • Substrates of CYP3A4 (e.g., cyclosporine, warfarin) and CYP2D6 (e.g., aripiprazole)
  • Substrates of CYP2C19 (e.g., omeprazole) and CYP2C9 (e.g., warfarin)
    • Can result in decreased levels of interacting drug. Avoid concomitant use if possible. If giving drugs concomitantly, monitor drug levels if possible.