Info
🌱 來自: polyuria
water diuresis
- Etiologies: DI (Na_serum >143) or 1° polydipsia (Na_serum <136) see “hypernatremia” above for list of causes of central and nephrogenic DI
- Workup of DI:
- Uosm <300 (complete) or 300-600 (partial)
- water deprivation test (rarely used)
- hypertonic saline-stimulated plasma copeptin >4.9 pmoL/L indicates 1° polydipsia (97% accuracy vs. 77% for water deprivation; NEJM 2018;379:428)