When to treat chronic HBV with anti-virals

(1) immune active phase; (2) HBeAg ⊖ chronic hepatitis B; (3) cirrhosis w/ HBV DNA ≥2K; (4) decomp. cirrhosis due to hep B; (5) acute liver failure due to acute hepatitis B; (6) special pop: preg (3rd trimester w/ HBV DNA ≥200k), inactive carriers treated w/ immunosuppression, HCC, HCV co-infection