Hyperprolactinemia

Etiology

• Prolactinoma (50% of pituitary adenomas)
• Stalk compression due to nonprolactinoma → ↓ inhibitory dopamine → ↑ PRL (mild)
• Physiology: PRL induces lactation and inhibits GnRH → ↓ FSH & LH
• etiologies
• Clinical manifestations:
  • amenorrhea,
  • galactorrhea,
  • infertility,
  • ↓ libido,
  • impotence
• Diagnostic studies of Hyperprolactinemia 󰒗
• Treatment 󰒖