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🌱 來自: Iron deficiency

Etiologies of Iron deficiency

chronic bleeding (GI—incl. cancer, menstrual, parasites, NSAIDs, etc.), ↓ supply (malnutrition; ↓ absorp. due to celiac sprue, Crohn’s, ↑ gastric pH, subtotal gastrectomy), ↑ demand (preg; Blood 2017;129:940). Iron-refractory iron-defic. anemia (IRIDA; rare genetic disorder due to hepcidin dysregulation; Nat Genet 2008;40:569).

  • 慢性出血(包括胃腸道出血,月經期間,寄生蟲感染,NSAID 等),
  • 供應不足(營養不良;由於乳糜瀉,Crohn 的病,胃 pH 升高, subtotal 胃切除而導致的 ↓ 吸收),
  • 需求增加(妊娠; Blood 2017;129:940)。
  • iron-refractory iron deficiency anemia 鐵難治性缺鐵性貧血(IRIDA;罕見的遺傳性疾病,由於肝鐵調素失調引起)