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🌱 來自: pharmocology

anticholinergics

anticholinergic medications where the anticholinergic activity is deemed to be therapeutic are listed below, along with the conditions they treat:

• Ipratropium and tiotropium: Function to dilate the bronchi and relieve shortness of breath and FDA approved for the use in patients with chronic obstructive pulmonary disease.[6]

• Benztropine and trihexyphenidyl: Used to counter reduced dopamine levels and relieve symptoms of Parkinson disease [6]

• Oxybutynin and tolterodine: FDA approved for the treatment of urge incontinence and detrusor hyperactivity[6]

• Oxybutynin has an off-label use for the treatment of hyperhidrosis.

• Diphenhydramine and other anti-histamines: FDA approved as a sleeping aid

• Scopolamine: Used as a prophylactic anti-emetic[8]

• Atropine: Used to dilate pupil during retina visualization and in the treatment of cholinergic toxicity[9]

• Vecuronium and Succinylcholine: Antinicotinic medications used as a neuromuscular blockade in surgeries[6]

• Mecamylamine: Used strictly in research settings as a ganglionic blocker[6]

• Glycopyrrolate: A type of quaternary amine used in anesthesia to decrease salivary and tracheal secretions[10]

• Medications like antipsychotics, tricyclic antidepressants, and diphenhydramine (when used to treat allergies) possess anticholinergic properties despite not being responsible for their therapeutic qualities.

Common peripheral adverse effects of medications with anticholinergic activity