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🌱 來自: Huppert’s Notes
Diabetes Prevention🚧 施工中
Diabetes Prevention
• Diabetes Prevention Program (DPP). N Engl J Med 2002;346(6):393–403.
- Multicenter, double-blind, randomized controlled trial that randomized 3234 middle-aged adults to intensive lifestyle counseling (dietary changes and 150 minutes of exercise per week for a weight loss goal of ≥7%) versus usual care. The intensive lifestyle counseling reduced the onset of diabetes by 58% compared to usual care. Metformin treatment reduced the onset of diabetes by 31%. These benefits persisted though the study’s 15-yr follow-up.