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from Etiologies-of thrombocytopenia

Peripheral Destruction-of-thrombocytopenia

Immune mediated

• 1°: ITP
• 2°:
  • Drugs
    • quinine,
    • vancomycin,
    • GPIIb-IIIa inhibitors),
    • vaccines (COVID-19),
  • infxn
    • HIV,
    • HCV,
    • EBV,
    • H. pylori
  • SLE,
  • APS,
  • lymphoproliferative disorders,
  • posttransfusion purpura,
  • IgA deficiency,
  • common variable immune deficiency,
  • ALPS,
  • neonatal alloimmune thrombocytopenia

Nonimmune

• MAHA
  • DIC,
  • HUS,
  • TTP,
• vasculitis,
• preeclampsia,
• HELLP syn,
• HD,
• cardiac bypass,
• IABP,
• hemangiomas