Info
Epidemiology of Diffuse large B-cell lymphoma
- Most common lymphoma type:
- ~30% of lymphomas,
- ~24K cases/y
- ↑ Incidence w/ age,
- ↑ incidence in Caucasians,
- slight male predominance
- Clinicopathologic Subtypes Clinical and Pathologic Subtypes
Many different subtypes (refer to updated 2016 WHO classification, Blood 2016;127:2375)
- Many different subtypes including 1° mediastinal (PMBL),
- 1° CNS (PCNSL),
- testicular,
- high-grade B-cell lymphoma w/ MYC & BCL2 &/or BCL6 translocations (HGBCL),
- transformed lymphoma,
- (2016 WHO classification, Blood 2016;127:2375)