infxns in immunosuppressed hosts

• Many Pts have ≥1 risk (eg, DM, ESRD, transplant, extremes of age)
• Accurate dx of opportunistic infections and targeted Rx key in this population
• The following is not an exhaustive list, but a delineation of common or classic etiologies

SEE: (NEJM 2007;357:2601; Am J Med 2007;120:764; CID 2011;53:798)

• Humoral immune dysfunction
• Granulocytopenia or neutropenia
• Impaired cell-mediated immunity
• Organ dysfunction
• Biologics