Info
🌱 來自: Folate deficiency
Etiologies of Folate deficiency
- malnutrition (alcoholics, anorectics, elderly),
- ↓ absorption (sprue),
- impaired metabolism (methotrexate, pyrimethamine, trimethoprim; NEJM 2015;373:1649),
- ↑ requirement (chronic hemolytic anemia, pregnancy, malignancy, dialysis)
- 營養不良(酗酒者、厭食症患者、老年人)
- 吸收↓(腸麻痺),
- 代謝受損(甲氨蝶呤、嘧啶、三甲氧苄噻嗪;NEJM 2015;373:1649),
- 需求↑(慢性溶血性貧血、懷孕、惡性腫瘤、透析)。