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🌱 來自: Folate deficiency

Etiologies of Folate deficiency

  • malnutrition (alcoholics, anorectics, elderly),
  • ↓ absorption (sprue),
  • impaired metabolism (methotrexate, pyrimethamine, trimethoprim; NEJM 2015;373:1649),
  • ↑ requirement (chronic hemolytic anemia, pregnancy, malignancy, dialysis)

  • 營養不良(酗酒者、厭食症患者、老年人)
  • 吸收↓(腸麻痺),
  • 代謝受損(甲氨蝶呤、嘧啶、三甲氧苄噻嗪;NEJM 2015;373:1649),
  • 需求↑(慢性溶血性貧血、懷孕、惡性腫瘤、透析)。