Info
catheter-directed pharmacomech
- low-dose lytic infused (eg, tPA 1 mg/h for 12–24 hr per catheter) + U/S or mech fragmentation of clot.
- Consider if hemodyn. compromise or high risk & not candidate for systemic lysis or surgical thrombectomy
- Preferred to systemic lytic by some centers.
- Also consider if intermediate-high risk and evidence of early hemodynamic deterioration (Circ 2014;129:479).
- Lack of data on hard outcomes.