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🌱 來自: polycythemia vera (PV)
prognosis of polycythemia vera (PV)🚧 施工中
prognosis of polycythemia vera (PV)
• Median survival w/ Rx ~13.5 y (Blood 2014;124:2507); ↑ age, WBC, additional acquired somatic mutations → worse prognosis (Haematol2013;160:251)
• Post-PV myelofibrosis (spent phase) occurs in 10–20% of cases, usually after 10 y
• Risk of transformation into acute leukemia (<2–5% lifetime)