Info

🌱 來自: Treatment-polyuria

desmopressin

• Desmopressin can cause hyponatremia, which can be life-threatening.
• Desmopressin is contraindicated in patients at increased risk of severe hyponatremia.
• Risk factors include excessive fluid intake, illnesses causing fluid/electrolyte imbalances, and use of certain medications.
• Serum sodium concentrations should be normal before starting or resuming desmopressin.
• Serum sodium should be measured within 7 days and ~1 month after starting therapy and periodically during treatment.
• Monitor serum sodium more frequently in patients ≥65 years and at increased risk of hyponatremia.
• If hyponatremia occurs, desmopressin may need to be temporarily or permanently discontinued.