Info
🌱 來自: Huppert’s Notes
GI Bleed🚧 施工中
GI Bleed
詳見Transfusion strategies for acute upper gastrointestinal bleeding. - Randomized controlled trial that randomized 921 patients with severe acute UGIB to a restrictive transfusion strategy (transfuse for Hgb <7 g/dL) or a liberal transfusion strategy (transfuse for Hgb <9 g/dL). The restrictive strategy reduced further bleeding, and a subgroup analysis revealed improved survival with the restrictive strategy for patients with cirrhosis and Child-Pugh A or B disease (but not Class C). Of note, exclusion criteria included massive exsanguinating bleeding, ACS, CVA/TIA, recent trauma/surgery, or LGIB.
詳見Clopidogrel with or without omeprazole in coronary artery disease.
- Double-blind, randomized controlled trial that randomized patients on clopidogrel and aspirin to receive omeprazole vs. placebo. Prophylactic PPI reduced the rate of upper GI bleed.