Info

🌱 來自: breast cancer

Histology-of-breast cancer

• Ductal:
  • Invasive ductal carcinoma (IDC) comprises 75% of all breast CAs
    • Unilateral
    • Mostly unifocal
• Lobular (ILC):
  • 10% of breast CAs, a/w germline or somatic CDH1 mts. Difficult to detect on MMG. Increased frequency of multifocal & bilateral dz, equivalent prog to IDC
• Mucinous, medullary breast cancer, papillary, adenocystic:
  • Favorable prog
• Metaplastic: Extremely unfav. prog
• Phyllodes tumor
  • Composed of stromal & epithelial elements; tx is → surgery w/ margins > 1 cm; ALND; adj. RT, or adj. chemo not indicated
• TILs:
  • A/w improved prog (J Clin Oncol 2013;31:860)
  • FinHER trial