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🌱 來自: mantle cell lymphoma

Staging & Work Up of mantle cell lymphoma

• Ann Arbor Staging w/ Cotswolds modifications (JCO 1989;7:1630) I, II, III, ABX

• Excisional or core bx preferred for initial dx, as w/ other lymphomas

• Staging primarily consists of cross-sectional imaging w/ either a CT scan of chest/abdomen/pelvis ± neck or a PET scan

• Peripheral nodal areas evaluated w/ physical exam

• Peripheral blood flow cytometry. Leukemic phase disease is common

• BM bx needed to complete staging. Marrow involvement ± leukemic phase are common

• Panendoscopy needed prior to initiation of therapy. GI tract commonly involved

• LP to evaluate for CNS involvement in pts w/ blastic morphology or CNS sx