Iron deficiency

(Lancet 2021;397:233)

• ↓ marrow iron & depleted body iron stores

• ↓ heme synthesis

• → microcytosis → anemia

• Special clinical manifestations:

  • angular cheilosis,口角炎
  • atrophic glossitis,萎縮性舌炎
  • pica (consumption of nonnutritive substances such as ice, clay), 嗜異性飲食（如攝取冰、黏土等非營養性物質）
  • koilonychia (nail spooning)勺狀指甲。
  • Plummer-Vinson syndrome (iron deficiency anemia, esophageal web & atrophic glossitis)

• Etiologies of Iron deficiency

• Diagnosis of Iron deficiency

• Treatment of Iron deficiency