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🌱 來自: cancer biology
mechanisms and sites of action of some of the drugs used in the treatment of cancer
Figure: 
- 6-MERCAPTOPURINE and 6-THIOGUANINE
- Inhibit purine ring biosynthesis
- Inhibit DNA synthesis
- PEMETREXED and METHOTREXATE
- Inhibit dihydrofolate reduction,
- block thymidylate and purine synthesis
- CAMPTOTHECINS ETOPOSIDE TENIPOSIDE DAUNORUBICIN DOXORUBICIN
- Block topoisomerase function
- HYDROXYUREA
- Inhibits ribonucleotide reductase
- 5-fluorouracil
- Inhibits thymidylate synthesis
- GEMCITABINE CYTARABINE FLUDARABINE 2-CHLORODEOX YADENOSINE CLOFARABINE
- Inhibit DNA synthesis
- PLATINUM ANALOGUES ALKYLATING AGENTS MITOMYCIN TEMOZOLOMIDE
- Form adducts with DNA
- L-ASPARAGINASE
- Deaminates asparagine
- Inhibits protein synthesis
- EPOTHILONES TAXANES VINCA ALKALOIDS ESTRAMUSTINE
- Inhibit function of microtubules