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🌱 來自: viral respiratory infections

Treatment of viral respiratory infections

• Influenza (A & B):
  • Neuraminidase inhib. (eg, oseltamivir);
  • must start w/in 48 h of sx for low-risk; for critically ill or immunosupp.,
  • start ASAP even if >48 h. Peramivir IV if unable to tolerate PO.
  • Endonuclease inhib. (baloxavir),
    • superior to oseltamivir in ↓ sx & viral load on 1st day of Rx,
    • but resistance emerging;
    • no data in severe influenza (NEJM 2018; 379:913)
• RSV:
  • can consider inhaled ribavirin in immunosupp,
  • but very expensive & rarely used