Info
🌱 來自: sjögren’s syndrome
Diagnostic studies of sjögren’s syndrome
- Autoantibodies: ⊕ ANA (95%), ⊕ RF (75%)
- Primary Sjögren’s:
- ⊕ anti-Ro (anti-SSA, ~50%) ± anti-La (anti-SSB, ~30%)
- Schirmer test:
- filter paper in palpebral fissures to assess tear production
- Rose-Bengal staining:
- dye that reveals devitalized epithelium of cornea/conjunctiva
- Ocular staining score:
- substitute for Rose-Bengal staining to determine degree of keratoconjunctivitis sicca using fluorescein and lissamine green
- Biopsy (minor salivary, labial, lacrimal, or parotid gland):
- lymphocytic infiltration