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Docetaxel
- Consider in high-volume metastatic dz (visceral mets or ≥4 bone mets w/ ≥1 outside vertebrae & pelvis). ADT+docetaxel 75 mg/m2 × 6 cycles. Prolongs OS vs. ADT alone. (NEJM 2015;373;737; JCO 2018;36:1080; Lancet 2016;387(10024):1163)
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