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epidemiology and risk factors of non-Hodgkin lymphoma (NHL)🚧 施工中

epidemiology and risk factors of non-Hodgkin lymphoma (NHL)

• 79 types of NHL, ~70,000 new cases/y; median age dx 65 y; ♂ predom; 85% B-cell origin

• Associated conditions: immunodeficiency (eg, HIV, posttransplant); autoimmune

disorders (eg, Sjögren’s, RA, SLE); infection (eg, EBV, HTLV-I, H. pylori)

• Burkitt lymphoma: (1) endemic or African (jaw mass, 80–90% EBV-related); (2) sporadic or American (20% EBV-related); (3) HIV-related