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🌱 來自：post-transplant_maintenance_therapy

coral

Outcome of patients with relapsed diffuse large B-cell lymphoma who fail second-line salvage regimens in the International CORAL study - PubMed

1. • Design: Phase - III
   • Multicenter trial
   • Not reported if randomized or open-label/blind
2. • Number of patients: 203
3. • Patients characteristics: Patients with relapsed and refractory diffuse large B-cell lymphoma who could not proceed to autologous stem cell transplantation
4. • Agent:
   • Intervention: Salvage chemotherapy
   • Control: Not reported
   • Dose: Not reported
5. • Treatment line: Third-line treatment
6. • Trial Acronym (if provided) or NCTId Number: CORAL trial (Collaborative Trial in Relapsed Aggressive Lymphoma)
7. • Comparison of outcomes:

Outcome	Third-line chemotherapy (%)	Transplanted (%)
PFS)	Not reported	Not reported
OS)	4.4 months	1-year OS of 41.6% for transplanted vs. 16.3% for not transplanted
RR)	39% overall response rate, 27% CR/CRu, 12% PR	Not reported