Eosinophilic esophagitis

(JAMA 2021;326:1310):

• often young/middle-aged ♂.
• Dx: >15 eos/hpf on bx, esoph dysfxn (ie, dysphagia, food impaction).
• Rx: 1st line is PPI (½ respond);

alternative (or if fail PPI) is 3Ds:

• 1st elimination Diet (Ø milk, soy, eggs, wheat, nuts, fish);
• if no Δ, Drugs (swallow inh steroids);
• if ongoing sx & stricturing, Dilation (Gastro 2020;158:1776).