Disorders of Peristalsis

  • Absent contractility (failed peristalsis);
  • distal esophageal spasm (uncord. peristalsis w/ simult. contractions);
  • hypercontractile esoph (high amp contract.; Rx w/PPI, nitrates/CCB/PDEi, TCA);
  • ineffective esophageal motility (↓ amp of distal esoph contractions;
  • seen in scleroderma, DM, hypothyroid.;
  • Rx w/ underlying disorder & w/ PPI)

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