Info
🌱 來自: Thalassemias
Treatment of Thalassemias
- folate;
- transfusions + Fe chelator [either deferoxamine (IV) or deferasirox (PO)];
- ? splenectomy if ≥50% ↑ in transfusions;
- gene therapy in development (NEJM 2018;378:1479);
- luspatercept (↓ SMAD signaling) in β-thal major (NEJM 2020;382:1219)