Info
Major clinical manifestations of seronegative spondyloarthritis
- Inflammatory back pain: SI joints (sacroiliitis), apophyseal joints of spine
- characterized by IPAIN
- a.m. stiffness,
- responsive to NSAIDs
- Peripheral arthritis:
- typically asymmetric, oligoarticular, large joints, lower >upper limbs;
- however, can be symmetric & polyarticular (thus, mimic RA), espec. in psoriatic arthritis
- Enthesitis: 是: 一種炎症性關節疾病，主要影響肌腱或韌帶連接到骨頭的 → 部位，造成 ↪ 疼痛、腫脹和功能障礙
- inflammation at ↣ site of tendon/ligament insertion into bone, esp Achilles,
- plantar fascia (calcaneal insertion),
- pre-patellar,
- elbow epicondyles
- Rigidity of spine:
- bamboo spine by X-ray, ankylosis due to progressive growth of bony spurs that bridge intervertebral disc
- Dactylitis:
- “sausage digit” inflammation of entire digit (joint + tenosynovial inflamm)
- Uveitis:
- anterior uveitis most common extra-articular manifestation in seronegative SpA;
- usually unilateral and p/w pain, red eye, blurry vision, photophobia