clinical manifestations of primary myelofibrosis (PMF)

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🌱 來自: primary myelofibrosis (PMF)

clinical manifestations of primary myelofibrosis (PMF)🚧 施工中

clinical manifestations of primary myelofibrosis (PMF)

(BJH 2012;158:453)

• Ineffective erythropoiesis → anemia; extramedullary hematopoiesis → massive splenomegaly (abdominal pain, early satiety) ± hepatomegaly

• Tumor bulk and ↑ cell turnover → fatigue, weight loss, fever, sweats