Info
Definition and classification system of seronegative spondyloarthritis
- Spondyloarthritis (SpA):
- group of inflammatory disorders that share common clinical manifestations:
- inflammatory spine disease,
- peripheral arthritis,
- enthesitis (see below),
- and extra-articular manifestations (primarily ocular and skin disease)
- group of inflammatory disorders that share common clinical manifestations:
- Seronegative = absence of autoantibodies
- Subtypes:
- ankylosing spondylitis (AS),
- psoriatic (PsA),
- reactive (ReA),
- IBD-assoc,
- juvenille SpA,
- and undifferentiated.
- Distinguished by axial vs. peripheral predominant involvement.