Treatment of Cryoglobulinemic vasculitis
(Blood 2017;129:289; J Inflamm Res 2017;10:49): Rx underlying disorder. Heme malig → chemoradiation; HCV → antivirals; CTD → DMARD/steroids ± RTX. Type I: plasma exchange if hyperviscosity; steroids, alkylating agents, RTX, chemo. For mixed cryo, steroids and RTX; CYC or plasma exchange for major organ involvement.