Diagnostic studies-chronic obstructive pulmonary disease

• CXR of Diagnostic studies-chronic obstructive pulmonary disease

• PFTs: obstruction: ↓↓ FEV1, ↓ FVC, FEV1/FVC <0.7 (no sig Δ post bronchodilator), expiratory coving of flow-volume loop; hyperinflation: ↑↑ RV, ↑ TLC, ↑ RV/TLC; abnormal gas exchange: ↓ DLCO (in emphysema)

• ABG: ↓ PaO2, ± ↑ PaCO2 (in chronic bronchitis, usually only if FEV1 <1.5 L) and ↓ pH

• Screen symptomatic Pts with spirometry; don’t screen if asx; screen for α1-AT deficiency